pictures for contemplation…

I decided to put together a page of the more interesting and relevant nueroimaging scans so that I, and anyone else, can refer to them easily as we continue to learn about all this.


Map of white matter volume deficits when comparing participants with schizophrenia with healthy volunteers (red voxels) and those with bipolar disorder with healthy volunteers (blue voxels), superimposed onto a single brain in standard stereotactic space. Green voxels indicate overlapping regions.The brain slices are oriented in the plane of the Talairach atlas; distance (mm) above or below the intercommissural line is inset in the upper left corner of each slice; the right side of the brain is depicted by the right side of each slice. Clusterwise probability of false-positive activation P=0.011 for schizophrenia v. healthy volunteers and P=0.008 for bipolar disorder v. healthy volunteers; expected number of false-positive tests 51 for each analysis.

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Map of grey matter volume deficits when comparing individuals with schizophrenia with healthy volunteers, superimposed onto a single brain in standard stereotactic space. The brain slices are oriented in the plane of the Talairach atlas; distance (mm) above or below the intercommissural line is inset in the upper left corner of each slice; the right side of the brain is depicted by the right side of each slice. Cluster-wise probability of false-positive activation P=0.003; expected number of false-positive tests <1 over the whole map.

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(A) A statistical parametric map showing significantly lower MTR in the right prefrontal subgenual cingulate cortex and subgyral white matter in bipolar patients compared with healthy controls in a ‘glass brain’ projection. (B) The same statistical parametric map (thresholded at T = 3.21) projected on orthogonal sections through a T1-weighted averaged image. The orthogonal lines cross at MNI coordinates [16, 24, –10] corresponding to the greatest MTR reduction.

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(A) A statistical parametric map showing significantly lower white matter density in bilateral frontal white matter in bipolar patients compared with healthy controls in a ‘glass brain’ projection. (B) The same statistical parametric map (thresholded at T = 3.21) projected on contiguous 2 mm thick axial T1-weighted averaged images, throughout the area of significantly lower white matter density. The numbers at the left bottom corner of each section represent the z MNI coordinate.

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2 Responses to “pictures for contemplation…”

  1. […] I have added a page with more neuroimaging scans. […]

  2. The studies you’re sourcing, are they basically rifs on the UCLA Study*, or are there others? If you’ve got it hanging around, this is the image I’m interested in — “white_matter_deficits.gif”, if you could send me the link to the study it came from I’d appreciate that as well.

    *sciencedaily.com/releases/2007/04/070411090315.htm

    All is going as well as it could be going… I’m gently trying to start CSN:AFU again, I figure that’s the blog where my salvation ultimately lies. And you?

    Next time you turn around say hi to your boyfriend for me.

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